Our mission is to improve people's lives by bringing bold ideas, rigorous science, and clinical expertise to the most important questions in health care.

Read more about our research

 

At the Smith Institute, we bring bold ideas, rigorous science, and clinical expertise to the most important questions in health care. Our multidisciplinary community of clinicians, methodologists, and data scientists is committed to generating trusted evidence and driving innovation that translate into better care, better policy, and healthier lives. 

Building on more than a decade of growth at Beth Israel Deaconess Medical Center (BIDMC) and across the broader Harvard community, the Institute comprises multiple centers pursuing distinct scientific missions, together strengthened by shared expertise and collaboration. The Institute's centers span clinical outcomes research, medical device innovation and evaluation, health policy, quantitative methods, and artificial intelligence. We pair the front-line insight of clinicians with state-of-the-science methods, grounding our research in the questions that matter most to patients, health systems, and policymakers. We train the next generation of research leaders to carry that work forward. 

We are deeply grateful to Richard A. and Susan F. Smith for the vision and generosity that support our shared goal: transforming health care and improving lives across the United States and around the world. 

 

Robert Yeh, MD, MSc, MBA, Executive Chair
Rishi Wadhera, MD, MPP, MPhil, Director

Health care costs reach a breaking point
New American Heart Association Presidential Advisory outlines contributors to and consequences of the current health care affordability crisis, proposes five guiding principles for action by lawmakers and policymakers.
PCORI awards full study phase of RAPTOR-CIED study to faculty investigators Daniel Kramer, MD and Issa Dahabreh, MD, MS, ScD
The Patient-Centered Outcomes Research Institute (PCORI) has approved the RAPTOR-CIED study to advance from its feasibility phase to the full study phase, following the successful completion of early project milestones.
Fellowship for Students Interested in Policy, Outcomes
The Joan and Marcel Zimetbaum Fellowship supports students interested in health policy and outcomes research in a unique one-year intensive program, providing foundational training in biostatistics & public health with faculty mentorship.
The Smith Center celebrates 10 years
The Richard A. and Susan F. Smith Center for Outcomes Research was officially launched on November 1, 2015. In tandem with the recruitment of Dr. Robert Gerszten, Dr. Peter Zimetbaum hired Dr. Robert Yeh (Director) to start a new center focused on outcome
Black Adults Treated for Common Arterial Disease are at Greater Risk of Amputation and Death than White Adults
In a nationwide analysis of Medicare beneficiaries, investigators documented racial differences in treatment and outcomes for patients with peripheral artery disease.
Program Award for a Culture of Excellence in Mentoring
The Harvard Medical School Office for Diversity Inclusion and Community Partnership has awarded the Smith Center with a 2022 Program Award for a Culture of Excellence in Mentoring for efforts to foster excellence, innovation & sustainability in mentoring.
Mental Health & Substance Use Among Homeless Adolescents
Research by Rishi Wadhera, MD, and Michael Liu, MPhil, found that homeless adolescents experienced significantly worse mental health and more substance use than their housed counterparts in the United States.
BIDMC Research Guides FDA Action on Common Medical Device
Research led by Eric Secemsky, MD, and Robert Yeh, MD and the FDA supports and updated device label and long-term program to monitor safety of a common aortic stent graft.

Zimetbaum Fellowship Applications Open!

Are you: 
A US medical student or resident?
Interested in health policy research? 

The Zimetbaum Fellowship provides dedicated mentorship in foundational biostats, outcomes research, and more! 

Application deadline: Friday, October 16, 2026